Full Title: Xenotropic murine leukemia virus-related virus prevalence in patients with chronic fatigue syndrome or chronic immunomodulatory conditions.
Authors: Henrich TJ, Li JZ, Felsenstein D, Kotton CN, Plenge RM, Pereyra F, Marty FM, Lin NH, Grazioso P, Crochiere DM, Eggers D, Kuritzkes DR, Tsibris AM.
Publication: The Journal of Infectious Diseases
Publication Date: 15th November 2010
Divisions of Infectious Diseases and Allergy, Immunology, and Rheumatology, Brigham and Women's Hospital, Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, and Dana-Farber Cancer Institute, Boston, Massachusetts.
We investigated the prevalence of xenotropic murine leukemia virus-related virus (XMRV) among 293 participants seen at academic hospitals in Boston, Massachusetts. Participants were recruited from the following 5 groups of patients: chronic fatigue syndrome, human immunodeficiency virus infection, rheumatoid arthritis, hematopoietic stem-cell or solid organ transplant, or a general cohort of patients presenting for medical care. XMRV DNA was not detected in any participant samples. We found no association between XMRV and patients with chronic fatigue syndrome or chronic immunomodulatory conditions.