Full Title: RNASEL alleles and susceptibility to infection by human retroviruses and hepatitis viruses.
Authors: Arredondo M, de Bethencourt FR, Treviño A, Collado A, Torres P, Barbolla L, Soriano V, de Mendoza C.
Hospital Carlos III, Infectious Diseases, Madrid, Spain; email@example.com.
Allelic variants at the RNASEL gene might predispose to viral infections. The allelic distribution at codon 462 was 139 (33.9%), 204 (49.8%) and 67 (16.3%) for RR, RQ and QQ, respectively in 410 individuals in Spain. There were no significant differences comparing 105 blood donors and 71 patients with HIV-1 infection, 27 with chronic hepatitis C, 67 with prostate cancer and 107 with chronic fatigue syndrome. In contrast, two-thirds of 18 patients with HTLV-1 infection and 15 with chronic hepatitis B harboured RR.
View the abstract in PubMed.