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Evaluating the results of the PACE trial

Full Title: Evaluating the results of the PACE trial

Publication: Phoenix Rising

Publication Date: 12th May 2012

In March 2011, a study in the UK into possible treatments for patients with ME/CFS (Chronic Fatigue Syndrome) was published in The Lancet. Called the PACE trial, it was based on the hypothesis that therapies with a psychological basis would be highly effective in treating the condition and significantly improve the prospects of most patients to return to normal health and functioning.

Patients were split into four groups: one had approximately 5 sessions of Specialist Medical Care (SMC) and nothing more: the other three groups had 3 or 4 sessions of Specialist Medical Care and approximately 12 to 15 sessions of Cognitive Behaviour Therapy (CBT), Graded Exercise Therapy (GET), or Adaptive Pacing Therapy (APT). CBT wasbased on the illness model of fear avoidance"(of activity); whilst GET was based on "the illness model of deconditioning and exercise avoidance". Under the NICE guidelines, CBT and GET are all that are available for ME/CFS under the NHS in the UK.

All but one of the assessments reported in the trial were subjective, and were carried out by means of questionnaires. Only one objective assessment was carried out and reported upon in the study the six-minute walking test, which measured how far the patients could walk in 6 minutes. Patients were assessed both at the start and at the end of the trial.

View the full 'Evaluating the results of the PACE trial' report.


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