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What is the ​mitochondrial DNA variation study about?

Led by: Dr Joanna Elson

Aims: To discover whether people with M.E./CFS have different patterns of mitochondrial DNA variation that could affect a person’s chances of developing the illness or act as a barrier to recovery.

Dr Elson says: “Mitochondria are the powerhouses of the cell, and mitochondrial DNA provides the codes for proteins that are essential for energy production. We want to see if patients with M.E./CFS have different patterns of mitochondrial DNA variation that could affect a person’s chance of succumbing to M.E./CFS or act as a barrier to recovery.”

Cost: £30,000. Action for M.E. is funding the project and would like to thank the ME Association for donating £5,000 toward it.

Length of study: 18 months

Study began: 2014

Background information: Announced during M.E. Awareness Week 2014 along with our immune responses study, this project was prioritised from a list of six potential projects following voting by Action for M.E. supporting members and our Research Panel.