One donation, twice the impact: The Big Give is back!

2 December 2025

Improving lives, accelerating understanding

The Big Give Christmas Challenge is back and this year, we're raising £135,000 to improve lives and accelerate understanding for anyone affected by ME.

By donating online through the Big Give's website, between midday 2nd - 9th December, your gift will be DOUBLED. One donation, TWICE the impact.

By donating to our campaign, you will help us to:

Improve the lives of adults and children affected by ME through our information, support, advocacy, and healthcare services.

Read Hattie & Mia's story

“When my daughter Mia’s health collapsed in August 2024, our lives changed almost overnight.”  

Accelerate understanding of ME by leading and delivering more genetics research studies, like DecodeME, and supporting the next generation of ME researchers through our Future Leaders Programme.

Throughout the week, we'll be sharing personal stories from people with lived experience across our website and social media channels, highlighting the real impact ME has on people's lives, and how our work and services have supported them.

We understand that not everyone will be in a position to donate, but even just sharing our campaign with friends and family makes a huge difference.

With your support, we're driving real change, delivering hope, and making a lasting impact for everyone affected by ME.

What your support has helped us achieve since last year's campaign

Thanks to your generous support, the money raised during our Big Give Christmas Challenge campaign, last year, helped us to:

  • Respond to over 1,100 requests for information and support from adults and children with ME. 91% had increased understanding of their rights and options following contact with us.
  • Continue to support younger researchers in the ME field through our Future Leaders Network and build on the initial results of our DecodeME study through our Genetics Centre of Excellence research partnership with the University of Edinburgh.
  • Provided 215 bursaries to people on low incomes, helping them to access specialist healthcare, including Doctors and Physiotherapists.
  • Launch an Essay Competition for Medical Students across the UK, helping ensure the next generation of Doctors understand ME and can better support their patients with ME.

We'll be announcing the winners of our essay competition during the Big Give campaign week, so follow us on social media to see how it improved understanding of ME for those students who took part!

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© 2025 Action for ME Charity registered in England and Wales: 1036419. Registered in Scotland: SC040452. Registered Companies House: 02906840
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